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Mus musculus (house mouse) mmu-miR-221-3p URS0000170CF4_10090

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mmu-mir-221: Mmu-mir-221 is a microRNA that has been found to be involved in lymphoid development and is differentially expressed between distinguishable lymphocyte cell types [PMC2244641]. In a study on DIO + LFD mice, mmu-mir-221 was found to be downregulated in DIO mice [PMC4571067]. Mmu-mir-221 is an interaction partner of TOX4 and MMU-MIR-376C [PMC6391818]. In another study, the expression levels of mmu-mir-221 were assessed in relation to lung disease, but no differential expression was detected [PMC4691205]. Mmu-mir-221 was used in standard curve reactions for miRNA assays [PMC7430632]. Mmu-mir-221* has a similar expression level compared to mmu-mir-221 [PMC3421232]. Mmu-mir-221 was found to be upregulated in white adipose tissue (WAT) after high-fat diet (HFD) feeding [PMC3319598]. The upregulation of mmu-mir-221 and the downregulation of the mmu-miR-200 family were consistent with previous studies on WAT after HFD feeding [PMC3319598]. Mmu-miR-30e*, mmu-miR34c, and mmu-miR1425p were identified as differentially expressed miRNAs with high degrees of connectivity in a network analysis involving mmu-mir-221 [PMC6833270]. References: [PMC2244641]: [PMC4571067]: [PMC6391818]: [PMC4691205]: [PMC7430632]: [PMC3421232]: [PMC3319598]: [PMC6833270]:

mRNA interactions 7 total

Genome locations

Gene Ontology annotations


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This sequence is found in 51 other species

  1. Alligator mississippiensis ami-miR-221-3p
  2. Anolis carolinensis Aca-Mir-221-P2a_3p (mature (guide))
  3. Bos taurus Bta-Mir-221-P2a_3p (mature (guide))
  4. Canis lupus familiaris Cfa-Mir-221-P2a_3p (mature (guide))
  5. Capra hircus miR-221
  6. Cavia porcellus cpo-miR-221-3p
  7. Cervus elaphus cel-miR-221
  8. Columba livia (rock pigeon) Cli-Mir-221-P2a_3p (mature (guide))
  9. Cricetulus griseus cgr-miR-221-3p
  10. Danio rerio (zebrafish) dre-miR-221-3p
  11. Dasypus novemcinctus (nine-banded armadillo) dno-miR-221-3p
  12. Daubentonia madagascariensis dma-miR-221
  13. Echinops telfairi Ete-Mir-221-P2a_3p (mature (guide))
  14. Equus caballus eca-miR-221
  15. Gadus morhua (Atlantic cod) Gmo-Mir-221-P2a1_3p (mature (guide))
  16. Gallus gallus (chicken) gga-miR-221-3p
  17. Gekko japonicus Gja-Mir-221-P2a_3p (mature (guide))
  18. Gorilla gorilla gorilla ggo-miR-221 (MIR221)
  19. Gorilla gorilla ggo-miR-221
  20. Haplochromis burtoni (Burton's mouthbrooder) abu-miR-221
  21. Homo sapiens hsa-miR-221-3p
  22. Latimeria chalumnae Lch-Mir-221-P2a_3p (mature (guide))
  23. Lepisosteus oculatus Loc-Mir-221-P2a_3p (mature (guide))
  24. Macaca mulatta mml-miR-221-3p
  25. Maylandia zebra (zebra mbuna) mze-miR-221
  26. Microcebus murinus mmr-miR-221
  27. Monodelphis domestica (gray short-tailed opossum) mdo-miR-221-3p
  28. Monopterus albus Mal-Mir-221-P2a1_3p (mature (guide))
  29. Neolamprologus brichardi nbr-miR-221
  30. Nomascus leucogenys (northern white-cheeked gibbon) nle-miR-221
  31. Ophiophagus hannah oha-miR-221-3p
  32. Oreochromis niloticus oni-miR-221
  33. Oryctolagus cuniculus ocu-miR-221-3p
  34. Oryzias latipes (Japanese medaka) ola-miR-221
  35. Otolemur garnettii oga-miR-221
  36. Ovis aries miscellaneous RNA
  37. Pan paniscus (pygmy chimpanzee) ppa-miR-221
  38. Pan troglodytes ptr-miR-221
  39. Papio hamadryas pha-miR-221
  40. Pongo pygmaeus (Bornean orangutan) ppy-miR-221
  41. Pundamilia nyererei pny-miR-221
  42. Rattus norvegicus (Norway rat) rno-miR-221-3p
  43. Saimiri boliviensis boliviensis (Bolivian squirrel monkey) sbo-miR-221
  44. Sarcophilus harrisii Sha-Mir-221-P2a_3p (mature (guide))
  45. Sphenodon punctatus (tuatara) Spt-Mir-221-P2a_3p (mature (guide))
  46. Taeniopygia guttata (zebra finch) tgu-miR-221-3p
  47. Takifugu rubripes fru-miR-221
  48. Tetraodon nigroviridis (spotted green pufferfish) tni-miR-221
  49. Tor tambroides miR-221-3p
  50. Xenopus laevis Xla-Mir-221-P2a4_3p (mature (guide))
  51. Xenopus tropicalis (tropical clawed frog) xtr-miR-221