ssc-miR-19b: Ssc-mir-19b is a microRNA that has been predicted to target various genes in different studies. In one study, it was predicted to target the transporter gene SLC6A6, while in another study, it was predicted to target GCLC, which is necessary for glutathione synthesis [PMC7426424]. Ssc-mir-19b was also found to be down-regulated in exosome-like vesicles and predicted to target NRF2 [PMC7426424]. In a different study, ssc-mir-19b was found to be activated in hpiPSCs compared with pEFs [PMC4934789]. Ssc-mir-19b is one of the six candidate miRNAs that play a role in the urea cycle [PMC5043173]. It has also been found to have higher expression levels in LP compared to NP [PMC5043173]. Furthermore, ssc-mir-19b has been shown to reduce the luciferase activity of the wild-type SIRT5 reporter [PMC5043173]. It has also been identified as one of the miRNAs that have stringent target sites along the PRRSV genome sequences [PMC9651005]. Ssc-mir-19b has been found to target TNFα and IL-20 in pigs [PMC4778948]. Additionally, ssc-mir-19b is located on chromosome X and is produced from the same precursor as ssc-miR-361-5p and ssc-miR-361-3p [PMC3579806]. It has also been identified as one of the differentially expressed miRNAs in various pig breeds such as Iberian breed and Landrace breed [PMC3555835]. In studies on PRV-infected cells, ssc-mir-19b was found to be downregulated [PMC4545981]. The differential expression of ssc-mir-19b has also been confirmed in PRV-infected PK-15 cells [PMC7329775]. Finally, ssc-mir-19b has been identified as one of the differentially expressed miRNAs in the CK and JK groups [PMC9275911].
Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset
View annotations in different species by clicking on species names.
Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.