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hsa-mir-188: Hsa-mir-188 is a cancer-related miRNA that has been associated with acute myeloid leukemia [PMC5558674]. High expression levels of hsa-mir-188 have been found to indicate a shorter patient survival time [PMC9019458]. The role of hsa-mir-188 in ovarian cancer remains undetermined [PMC5945511]. Hsa-miR-188 has been shown to inhibit the proliferation, migration, and invasion of glioma by suppressing the expression of IGF2BP2 [PMC7946859]. The target genes of hsa-miR-3677 and hsa-miR-188 have been predicted using mirDB and WGCNA [PMC8298461]. A precursor expression vector for hsa-miR-188 has been constructed for further study [PMC7844764]. HSA-MIR 188 is part of a cluster on human chromosome X that includes other genes such as HN 11, HP 77, HN 12, and HN 13 [PMC1315341]. The upregulation of all seven miRNA members in the hsa-MIR 188 cluster has been observed in certain conditions [PMC4665306]. MicroRNA present in autism-associated CNVs may play a role in disease phenotype determination or contribution to autism spectrum disorders [PMC3581547].
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