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Gallus gallus (chicken) gga-miR-383-5p URS00000C5969_9031

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gga-mir-383: Gga-mir-383 is a specific miRNA that targets the 3′UTR region of cDNMT3B [PMC3086922]. In a study examining the regulation of cDNMT3B expression, gga-mir-383, along with gga-miR-15c, gga-miR-29b, and gga-miR-222, was selected for analysis [PMC3086922]. The expression levels of these miRNAs were examined during meiotic stages of germ line development using qRT-PCR [PMC3086922]. The study found that gga-mir-383, along with gga-miR-29b and gga-miR-222, may cause significant downregulation of cDNMT3B in vitro [PMC3086922]. Additionally, the study generated mutants for each miRNA binding site in the cDNMT3B 3′UTR and found that gga-mir-383 resulted in a slight decrease in cDNMT3B expression [PMC3086922]. The regulation of cDNMT3B using these miRNAs is of great interest in this study [PMC3086922]. Furthermore, another study examined the expression patterns of various miRNAs during meiotic stages of germ line development and found that the expressions of gga-miR-15c, gga-mir-383, and gga-miR-222 were increased after E11.5 in males [PMC3086922]. These findings suggest that these miRNAs may downregulate cDNMT3B in vivo in both male and female chickens during germ line development [PMC3086922]. In another analysis comparing different groups (NC versus CS and CM versus CS), it was found that only three miRNAs (including gga-mir-383) were significantly differently expressed in all three groups [PMC5203650]. The expression patterns of gga-miR-21, gga-miR-146b-5p, gga-miR-146b-3p, gga-miR-429, and gga-miR-215 were comparable to the sequencing results [PMC5203650].

Genome locations

Gene Ontology annotations


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This sequence is found in 58 other species

  1. Alligator mississippiensis Ami-Mir-383-v1_5p (mature (guide))
  2. Anolis carolinensis (green anole) Aca-Mir-383-v1_5p (mature (guide))
  3. Bos taurus bta-miR-383
  4. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-383a
  5. Canis lupus familiaris cfa-miR-383
  6. Cavia porcellus cpo-miR-383-5p
  7. Chrysemys picta bellii (western painted turtle) Cpi-Mir-383-v1_5p (mature (guide))
  8. Chrysemys picta cpi-miR-383-5p
  9. Columba livia (rock pigeon) Cli-Mir-383-v1_5p (mature (guide))
  10. Dasypus novemcinctus (nine-banded armadillo) dno-miR-383-5p
  11. Echinops telfairi Ete-Mir-383-v1_5p (mature (guide))
  12. Equus caballus eca-miR-383
  13. Gekko japonicus Gja-Mir-383-v1_5p (mature (guide))
  14. Homo sapiens (human) hsa-miR-383-5p
  15. Macaca mulatta (Rhesus monkey) mml-miR-383
  16. Microcaecilia unicolor Mun-Mir-383_5p (mature (guide))
  17. Monodelphis domestica mdo-miR-383-5p
  18. Ophiophagus hannah (king cobra) oha-miR-383-5p
  19. Ornithorhynchus anatinus (platypus) Oan-Mir-383-v1_5p (mature (guide))
  20. Oryctolagus cuniculus ocu-miR-383-5p
  21. Pan troglodytes (chimpanzee) ptr-miR-383
  22. Pongo pygmaeus ppy-miR-383
  23. Pteropus alecto pal-miR-383-5p
  24. Python bivittatus pbv-miR-383-5p
  25. Sarcophilus harrisii Sha-Mir-383-v1_5p (mature (guide))
  26. Sphenodon punctatus (tuatara) Spt-Mir-383_5p (mature (guide))
  27. Taeniopygia guttata tgu-miR-383-5p
  28. Xenopus laevis (African clawed frog) Xla-Mir-383-P1_5p (mature (guide))
  29. Xenopus tropicalis (tropical clawed frog) xtr-miR-383