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Bos taurus (cattle) bta-miR-19a URS000006FDD4_9913

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bta-mir-19a: Bta-mir-19a is a differentially expressed (DE) miRNA that is upregulated in both non-pregnant and pregnant cows, along with bta-mir-19b, while several other miRNAs, including bta-miR-30a-5p and various bta-miR-2284 families, are downregulated [PMC7458322]. Bta-mir-19a and bta-miR-19b are associated with various biological functions such as cytoskeleton organization, cell junction formation, vasculogenesis, cell proliferation, oxidative stress response, immune response regulation, and ATP synthesis [PMC7458322]. In a transcriptome analysis of miRNAs using RNA sequencing in cows, bta-mir-19a is one of the 11 differentially expressed miRNAs found in both pregnant and non-pregnant cows [PMC7458322]. Bta-mir-19a has been reported to target genes such as HSPBAP1, DNAJB1, HPX (heat stress response genes), PLA2R1 (involved in heat stress response through oxidation), and PICEN [PMC7458322]. In a comparison of differentially expressed miRNAs between groups of cows (non-pregnant vs. pregnant), several DE miRNAs were identified including bta-mir-221 (shared between all groups), bta-mir-1247-5p (in H_SCM comparison), and 9 DE miRNAs in the ARM_SCM comparison [PMC10000098]. Bovine studies have also associated other candidate miRNAs such as bta-miR-21-5p with Wnt signals and MAPK pathway regulation [PMC9445238].

Genome locations

Gene Ontology annotations


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This sequence is found in 52 other species

  1. Alligator mississippiensis (American alligator) Ami-Mir-19-P1a_3p (mature (guide))
  2. Anolis carolinensis Aca-Mir-19-P1a_3p (mature (guide))
  3. Ateles geoffroyi (black-handed spider monkey) age-miR-19a
  4. Callithrix jacchus cja-miR-19a
  5. Callorhinchus milii Cmi-Mir-19-P1a-v1_3p (mature (guide))
  6. Canis lupus familiaris cfa-miR-19a
  7. Capra hircus chi-miR-19a
  8. Cavia porcellus (domestic guinea pig) cpo-miR-19a-3p
  9. Cervus elaphus cel-miR-19a
  10. Chrysemys picta bellii (western painted turtle) Cpi-Mir-19-P1a_3p (mature (guide))
  11. Columba livia cli-miR-19a-3p
  12. Cricetulus griseus (Chinese hamster) cgr-miR-19a
  13. Danio rerio dre-miR-19a-3p
  14. Dasypus novemcinctus dno-miR-19a-3p
  15. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-19-P1a_3p (mature (guide))
  16. Equus caballus (horse) eca-miR-19a
  17. Gadus morhua (Atlantic cod) gmo-miR-19a-3p
  18. Gallus gallus (chicken) gga-miR-19a-3p
  19. Gekko japonicus Gja-Mir-19-P1a_3p (mature (guide))
  20. Gorilla gorilla gorilla ggo-miR-19a (MIR19A)
  21. Gorilla gorilla ggo-miR-19a
  22. Homo sapiens (human) hsa-miR-19a-3p
  23. Lagothrix lagotricha (brown woolly monkey) lla-miR-19a
  24. Latimeria chalumnae Lch-Mir-19-P1a_3p (mature (guide))
  25. Lemur catta (Ring-tailed lemur) lca-miR-19a
  26. Macaca mulatta mml-miR-19a-3p
  27. Macaca nemestrina (pig-tailed macaque) mne-miR-19a
  28. Microcaecilia unicolor Mun-Mir-19-P1a_3p (mature (guide))
  29. Monodelphis domestica (gray short-tailed opossum) mdo-miR-19a-3p
  30. Monopterus albus Mal-Mir-19-P1a2_3p (mature (guide))
  31. Mus musculus (house mouse) mmu-miR-19a-3p
  32. Nomascus leucogenys (northern white-cheeked gibbon) nle-miR-19a
  33. Ophiophagus hannah oha-miR-19a-3p
  34. Ornithorhynchus anatinus oan-miR-19a-3p
  35. Oryctolagus cuniculus (rabbit) ocu-miR-19a-3p
  36. Ovis aries (sheep) miscellaneous RNA
  37. Pan paniscus (pygmy chimpanzee) ppa-miR-19a
  38. Pan troglodytes (chimpanzee) ptr-miR-19a
  39. Pongo pygmaeus (Bornean orangutan) ppy-miR-19a
  40. Python bivittatus pbv-miR-19a-3p
  41. Rattus norvegicus (Norway rat) rno-miR-19a-3p
  42. Saguinus labiatus (red-chested mustached tamarin) sla-miR-19a
  43. Sarcophilus harrisii (Tasmanian devil) Sha-Mir-19-P1a_3p (mature (guide))
  44. Scyliorhinus torazame Sto-Mir-19-P1a-v1_3p (mature (guide))
  45. Sphenodon punctatus (tuatara) Spt-Mir-19-P1a_3p (mature (guide))
  46. Sus scrofa (pig) ssc-miR-19a
  47. Takifugu rubripes (torafugu) fru-miR-19a
  48. Tetraodon nigroviridis tni-miR-19a
  49. Tor tambroides miR-19a-3p
  50. Tupaia chinensis tch-miR-19a-3p
  51. Xenopus laevis (African clawed frog) Xla-Mir-19-P1a4_3p (mature (co-guide))
  52. Xenopus tropicalis xtr-miR-19a