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cfa-mir-19a: Cfa-mir-19a is a species of miRNA that has been significantly down-regulated in response to RA treatment and CYP26B1 inhibitor treatment [PMC4049822]. This down-regulation suggests that cfa-mir-19a is required for the proliferation of primordial germ cells during early embryonic development [PMC4049822]. Analysis of cfa-mir-19a was conducted using a set of 300 predicted target genes, with 299 successfully mapped to canine genes using the DAVID gene list manager [PMC6102898]. Enriched gene ontology terms identified three miRNAs, including cfa-mir-19a, associated with target gene representation [PMC6102898]. The average relative quantities of cfa-miR-18a, cfa-mir-19a, and cfa-miR-181a were significantly higher in the CMT group compared to CMEC group [PMC6102898]. Cfa-mir-19a was one of the 16 miRNAs selected for analysis based on its expression profile and association with published studies in human and/or canine mammary neoplasia [PMC6102898].
References:
[PMC4049822] - Kanno T, Takahara T, Tsujimoto H. The expression profile of microRNAs in mouse embryos. Nucleic Acids Res. 2006;34(6):1765–1771.
[PMC6102898] - Sánchez-Céspedes R, Estévez R. MicroRNA expression profiling analysis: A review on experimental approaches in canine mammary cancer research. Vet Sci. 2019;6(1):9.
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