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rno-mir-19a: Rno-mir-19a is a type of microRNA that has been studied in various contexts. In one study, the sequences of rno-mir-19a mimics were identified as 5′-UGU GCA AAU CUA UGC AAA ACU GA-3′ and 5′-AGU UUU GCA UAG AUU UGC ACA UU-3′ [PMC5247685]. Another study found that rno-mir-19a, along with rno-miR-19b-2, rno-miR-137, and rno-miR-214, were downregulated at all four time-points [PMC5064799]. These miRNAs were predicted by multiple databases and selected for validation [PMC5064799]. The expression of rno-mir-19a, along with rno-miR-137, rno-miR-19b2, and rno-miR214, as well as their target genes EGR2 and ARC, were shown to be regulated by propofol in primary cultured embryonic NSCs [PMC5064799]. The fold-change in the mean expression levels of these miRNAs ranged from -2.33 to -6.68 for rno-mir19a [PMC5064799]. Additionally, another study found that exosomes derived from MSCs overexpressing GATA4 were enriched in rnomir19a and may promote increased cardiac muscle cell survival in a hypoxic environment [PMC6406975]. These findings suggest that propofol may have the ability to regulate the expression of rnomir19a and other miRNAs in various contexts.
mRNA interactions
2 total
Genome locations
Gene Ontology annotations
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Localisation
Sequence
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