hsa-let-7e: Hsa-let-7e (MIMAT0000066) is one of the primers used in the study [PMC3821025]. The study found that DIM, a compound, can inhibit the expression of EZH2 in castration-resistant prostate cancer [PMC6222788]. This inhibition is achieved by up-regulating hsa-let-7e, which is ranked at 13th among the primers used [PMC6222788]. The up-regulation of hsa-let-7e by DIM leads to a decrease in EZH2 expression [PMC6222788]. This finding suggests that hsa-let-7e may play a role in regulating EZH2 expression in castration-resistant prostate cancer [PMC6222788]. Further research is needed to fully understand the mechanism by which hsa-let-7e regulates EZH2 and its potential therapeutic implications for castration-resistant prostate cancer [PMC6222788].
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