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Sus scrofa (pig) ssc-miR-210 URS000055128B_9823

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ssc-mir-210: Ssc-mir-210 is a microRNA that participates in the regulation of the Neurotrophin signaling pathway by targeting corresponding genes such as BNDF, SHC4, KRAS, and FOXO3 [PMC4934789]. It is upregulated in renal cell carcinoma and is associated with the upregulation of EPAS1, EGLN3, EGLN1, and VEGFC [PMC4646468]. Ssc-mir-210 is induced by HIF1α under hypoxic conditions in mice [PMC4646468]. It has been shown to stabilize HIF1A and attenuate hypoxia-induced apoptosis, angiogenesis, and stress response in mammalian cells [PMC9674649]. Ssc-mir-210 has also been found to be differentially expressed after acute H-R stress in thalamus cells [PMC9674649]. It is mainly expressed in the liver, spleen, and stomach but also found in other tissues such as the brain and lungs [PMC3427155]. Ssc-mir-210 has been identified as a key miRNA involved in various biological processes [PMC8529057]. It is one of the most frequently expressed miRNAs across different samples [PMC6090871]. However, it was not among the miRNAs associated with PRRSV infections studied in a particular research project [PMC9651005]. Ssc-mir-210 plays a regulatory role in adipocytes along with other miRNAs such as ssc-miR-145-5p and novel-miR-126 [PMC8834144]. The expression differences of ssc-mir-210 have been validated using qRT-PCR along with other genes and miRNAs such as AGT, GK, CAT ssc-miR-874 ssc-miR-370 ssc-miR129b[ PMC8834144].

Genome locations

Gene Ontology annotations

Sequence

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CUGUGCGUGUGACAGCGGCUGA

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This sequence is found in 24 other species

  1. Bos taurus (cattle) Bta-Mir-210_3p (mature (guide))
  2. Branchiostoma belcheri (Belcher's lancelet) bbe-miR-210-5p
  3. Branchiostoma floridae bfl-miR-210-3p
  4. Branchiostoma lanceolatum Bla-Mir-210_3p (mature (guide))
  5. Canis lupus familiaris (dog) Cfa-Mir-210_3p (mature (guide))
  6. Capra hircus (goat) miR-210
  7. Cavia porcellus cpo-miR-210-3p
  8. Cricetulus griseus cgr-miR-210-3p
  9. Dasypus novemcinctus dno-miR-210-3p
  10. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-210_3p (mature (guide))
  11. Gorilla gorilla gorilla ggo-miR-210 (MIR210)
  12. Gorilla gorilla (western gorilla) ggo-miR-210
  13. Homo sapiens hsa-miR-210-3p
  14. Macaca mulatta (Rhesus monkey) mml-miR-210-3p
  15. Mus musculus (house mouse) mmu-miR-210-3p
  16. Nomascus leucogenys (northern white-cheeked gibbon) nle-miR-210
  17. Oryctolagus cuniculus (rabbit) Ocu-Mir-210_3p (mature (guide))
  18. Otolemur garnettii (small-eared galago) oga-miR-210
  19. Ovis aries (sheep) miscellaneous RNA
  20. Pan paniscus ppa-miR-210
  21. Pan troglodytes ptr-miR-210
  22. Papio hamadryas pha-miR-210
  23. Rattus norvegicus rno-miR-210-3p
  24. Tupaia chinensis (Chinese tree shrew) tch-miR-210
Publications