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Homo sapiens (human) MRPL20 divergent transcript (MRPL20-DT) URS00022AE7E2_9606

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MRPL20-DT: MRPL20-DT is a long non-coding RNA (lncRNA) whose role is still undetermined, but there is evidence suggesting its possible association with cancer [PMC10003012]. A recent study found that the promoter of MRPL20-DT is consistently upregulated across 13 different tumors [PMC10003012]. In addition, three other lncRNAs, ENSG00000235904 (RBMS3-AS3), ENSG00000261472 (Novel transcript), and ENSG00000272455 (MRPL20-DT), showed consistent dysregulation in these tumors, with RBMS3-AS3 and the Novel transcript being upregulated and MRPL20-DT being downregulated [PMC10003012]. The lncATLAS database did not provide any information about the localization of MRPL20-DT [PMC10003012]. Interestingly, TANRIC's survival analysis showed that higher expression of MRPL20-DT was associated with better survival probability in bladder cancer patients [PMC10003012]. Furthermore, a study identified 15 exosome-related lncRNAs, including MRPL20-DT, which could be used for further investigation [PMC9789946]. Based on the expression levels of these 15 lncRNAs and their regression coefficients, a prognostic signature was established to assess the overall survival of bladder cancer patients [PMC9789946]. References: - PMC10003012 - PMC9789946

Genome locations

Gene Ontology annotations

Sequence

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AGUUUCUUUAUAACAGUUUAUUAUACUUGGAUAUUUUUUAAAUCAUAGAAGAGUUGGAAUACAAGUACAAGGAAAACUCCCCAGUGUUCACUACCAAAAUGUGCCAGCUGUUUUCAUUUGUUCCAUUUGUUUAAUACUCUCGAACCAAAUUCACCUACUAUUUACGUUUUGCUCCAUUUUUGAAUCAUUCUCUCUGUAAAUAUAAACAUAAUGGAUUUUUUUCCUAAACCAUUUGAGACGCUGGAGACACCUAAACACUUUGCUGUGUAUUUACUCUUAGGAACCACACCGUAGAAUGGUCAAAAUCCGGACCCAGCCCACACUCCAGAUUUAACUCGCUUCAAAUGUCUUUUAUACCUUUUUUUCCCUGUUGAGGAUUCAGUCUAGGAUGACGCACUGCAUUUGUUGUUGUGUUUCUUGUUUUGUUUUGUUUUUUUCUGUUUUUGAGACGGAGUUUUGCUCCGUCGCCCAGUCUGGAGUACAAAGGUGCGAUCUCGGCUGACCGCAACCUCUGCCUACCCGGUUCAAGUGAUUCUCCUGCCUCAGCCUCCCGAGUAUCUGGGAUUACAGGCGCACACCGCCACUCCCAGCUAAUUUUUGUAUUUUUAGUAGAGACGGGAUUUCACAAUGUUGGCCAGGCUGGUCUCGAACUCCCGACCUUAAAUGACCAGGCUGACCAACAUGGUCAGCUACUCAGGAGGCUGAGGCAGGAGAAUCGCUUGAACCCGGGAGGCAGAGUUUGCGGUGAGCCGAGAUCCCGCCAUUCAUUGCACUCCAGCCUCGGAAACUAGCAAAACUCCAUCUUAAAAAAAAAGAGGAGGCCGGGUGCAGUGGCUCUGCACAACACUUUGGGAGGCCGAGGCAGGUGGAUCACCUGAGGUCAGAAAUCCGAGACCAGCCUGGCCAACAUGGUGGAACCCCAUCUCUACUAAAAAUGCAAAAAGUAGCCGGGCGUGGUAGCGGGCCCCAGUAAUCCCAGCUGAGGUGGGAGAAUUGCUUGAACCCGGGAGGCCAAGGCUGCAGUGAGCCAAGAUCGCACCACUGCACUCUAGCGUGGGUGACAGAUCAAGACCUUGUCUCAAAAAACAAGAAGAAGAAAAACUACUUUUUUUUUUUCAGAUGGGGUCUCACUCUCACCCAGUCUGGAGUGCAGUGGCGCCAUCUCAGCUCAUUGCAGCCUCUGCCUCCUGGGCUUGAGUGAUCUUCCCACCUCGACCUCCUGAGUAGCUGAACCACAAGUGCAUGCCUGGCCAAUUUUUGUAUUUUUGGUAGAAAUGGAGUUUCACCAUGUUGCCCAGGCUGGUCUCAAAACUGGCCUCCCAAAGUGCUGGGAUUACAGACACAACUGGCCUACCUGCAGGAUUUUCAGUUUAUGGACAUGACUGACUGGAGACAUGGAGAAGCUGUUGUUAUUGGAGAUUUUUAUUACUCGCAUUUCCUGAGCGAUGGGGACACUCACUGUGGGGAAAAGCAAGAGAGAUCAGAUUGUUACUGUGUCUGUGUAGAAAGAAGUAGACAUAGGAGACUCCAUUUUGUUCUGUACUAAGAAAAAUUCUUCUGCCUUGGGAUCCUGUUGAUCUGUGACCUUACCCCCAACCCCGUGCUCUCUGAAACAUGUGCUACGUCCACUCAGGGUUAAAUGGAUUAAGGGCGGUGCAAGAUGUGCUUUGUUAAACAGAUGCUUGAAGGCAGCACGCUCCUUAAGAGUCAUCACCACUCCCUAAUCUCAAGUACCCAGGGACACAGAAACUGCGGAAGGCCGCAGGGUCCUCUGCCUAGGAAAGCCAGGUAUUGUCCAAGGUUUCUCCCCAUGUGAUAGUCUGAAAUAUGGCCUCGUGGGAAGGGAAAGACCUGACCGUCCCCCAGCCCGACACCCGUAAAGGGUCUGUGCUGAGGAGGAUUAGUAUAAGAGGAAGGAAUGCCUCUUGCAGUUGAGACAAGAGGAAGGCAUCUGUCUCCUGCCUGUCCCUGGGCAAUGGAAUGUCUCAGUAUAAAACCCGAUUGUAUGUUCCAUCUACUGAGAUGGGGAAAAACCGCCUUAGGGCUGGAGGUGGGACCCGCGGGCAGCAAUACUGCUUUGUAAAGCAUUGAGAUGUUUAUGUGUAUGCAUAUCUAAAGCACAGCACUUAAUCCUUUACAUUGUCUAUGAUGCAAAGACCUUUGUUCACGUGUUUGUCUGCUGACCCUCUCCCCACAAUUGUCUUGUGACCGUGACACAUCCCCCUCUUUGAGAAACACCCACAAAUGAUCAAUAAAUACUAAGGGAACGCAGAGGCUGGCGGGAUCCUCCAUGUGCUGAACGCUGGUUCCCCGGGUCCCCUUAUUUCUUUCUCUAUA

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Publications