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Homo sapiens (human) TNF and HNRNPL related immunoregulatory long non-coding RNA (THRIL) URS000075D66B_9606

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THRIL: The lincRNA THRIL, a long intergenic non-coding RNA, has been studied in various contexts [PMC7884443]. The THRIL study (126) demonstrated that Treg infusion in liver transplant recipients was safe [PMC7884443]. In the context of Kawasaki disease, the expression levels of THRIL were found to correlate with disease severity [PMC7520417]. It was discovered that THRIL induced the expression of TNF-α by forming a ribonucleoprotein (RNP) complex with hnRNPL [PMC7520417]. Additionally, researchers aimed to investigate whether THRIL played a role in the regulation of the AKT pathway. To do so, they measured the expression of AKT under various situations by western blotting [PMC7488174]. These studies provide insights into the potential functions and mechanisms of action associated with THRIL in different biological contexts [PMC7884443][PMC7520417][PMC7488174].

Genome locations

Gene Ontology annotations

Sequence

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UGUUGGGAUUAUAGGGGUGAGCCACCCUGCCCAGCCUGCUCCAGCAAAUCUUAAAUAUCCAUGCACACUGAAUAAACAUGCACCUGAAACAGGUGCACGUUUCAGGAAGUGAAUGGAACUCUCCAGGAGAGUUUGGGUCCCAUCAUGUGUACCUUAGAAACAGAAGUCUCAAAAGUCUCAACAACAUCCACAAAAACAUCUGCAUCUGUUUUCCAGAUACUUGCAACCAAAAAUAAAACUUCACAGGAACACUACACAAGAAGUGGUAGACAGCUAAAUCUUCUCCAAACUGAGACCUGGACCAUAAGGUCUUGGUUGUAGCAGGUCUGGCAGGGGUUAUCUAUAAACCUGCACGCAGGGCACUGUGAGCGGGUUGCCAGGGUACAUCUGUGGCCAGGUAAGGGCCACAGAGACAGUCGUGAUCCCCAGCAGCUUCAAAGCUGCAAAAUGCUGGGCUUUUUUUUUUUUUUUUAAGAUGAAGUCUUGCUCUGUUGCCUAGGCUGGAGUGCAGUGGCGUGAUCUCGGCUCACCGCAACCUCCACCUCCCAGGUUCAAGCAAUUCUCCUGCCUCAGCCUCCUGAGUAGCUGGACUACAGGCACCCACCACCAUGCCUGACUAAUUUUUGUAUUUUUAGUAGAGACGGGGGUUUCACCAUGUUGGCCAGGCUGGUCUUGAACUCCUGACCUCAGGUGAUCCAUACUCCUCGGCCUCCCAAAGCGCUGGGAUUACAGGCAUCAGCCACUGCGCCUGGCCUAGGGCUUUCUUUUUUAAAAAACAAGUCCUAACAAAAGGGGGUUUCUACCAGCCCCUGAGCCACACCUUCUGAAACUCCCUUGCCCAGGAUCCCCACAGCUGUCCACCUCGCAAGUCCCACUCUCUGCCCACAGAGACUGCCUAAAAGGAGGACACAACAGAUUUCAGAUAAAAAGCACCUGUGUAUCGUAAAUAUUUCAGGAAAAAGAAUUCAGAUCUUUUCAAAGGCUUGCUUAUUGCUGCUAAUUGUUCCUGAGGAUCUUUCUAAGCAGCAAUAUACUUGAGAAUAUUAGCUGCUACUGUUUGUUUUCCCUCUAAGGUCCUGAGGAAAUCAAAAGAAAAAAAAAAAAACCCUCAAGGGUAUAGCUUUUGUAUAUAGCCCUAGUGAGCAAACUGCAAAUUGGGACAUGCAGUAGAUUCUGGAGCAAUCUCCAAUCCUUACCAGGUACUUCCUGGCAUCAAAUCCCCAGGACAUUUCUUGGCCCCUCCUUGCAUUUUCCGUUUCAAAAUGUUGAGGUUAAAAUACAUCGAAGCACAGAGGGAAGAAAAUCUCAGGUCUUCUAGAAAUGGCGAUGUCUUCAUUUAAAAAUAGGACUGAUGGGGGCUUGGCAGGGGUCUCUAGGAUCCAAAAGAGGUUGAGUUGCAUCCUGCAGCCCAACUGUCCACAUUUAGAAGUGACAACAUUCAUGAACUAAGUCAACAUCCACCAAAAAUAACAUGAAAUAAAGCUCACAGUUUGGGAACAUGAAAAUAACGCACACAGACCUCACCCACCAAUCCCUAAGCUGUGAAAACAAACGCUCGCAUUUAAACUUUUCUCAAAUGUCAAAUUAGCAUAUUCUUCCCCUCCAUGUAAAGUUUUAAUAAACUUGACUCAAUCUGCCUUUAUUAAAAAACCUUACAAAAGAUGUAUUUAAAUGCUUGAAAAAAUUAACUUUAUGCUCUAUGCACAGAUAAAUUUCUCUUACUGUACAACUAAAUAUGGUUAUAUCCUUUGUUUAAAAAAUAUUUUUUCCCCCACUAAUUACACUUCGUGUGUAGUUCCACGUCAAUGAUCUUUCCGCUCUUCUGGGAAUGUGUCCUAAGAGCUGCCGGGUGGGUGGAAAUAGCCCUACACAGCGCCACUUUCUUGCUCAGUCGUGUUUAUUAAGAUUGUUUGGGGUUUGGGGUUUUUUUCCUCCGUUUUCGUUUUCUGAGACAGCGUGCUGGUAACUGUGGACCCGCCCG

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Publications