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Homo sapiens (human) FGF14 intronic transcript 1 (FGF14-IT1) URS000075D011_9606

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FGF14-IT1: FGF14-IT1 is a long non-coding RNA (lncRNA) that has been identified as a potential diagnostic marker in various conditions. In the context of SARS-CoV-2 infection in infertile men, FGF14-IT1, along with eight other testis-specific lncRNAs, has been suggested as a diagnostic possibility [PMC9530275]. In osteosarcoma (OS) samples, FGF14-IT1 was found to be downregulated compared to normal bone samples [PMC9680297]. Additionally, FGF14-IT1 was found to encode micropeptides [PMC9680297]. The expression of FGF14-IT1 was also found to be downregulated in OS samples compared to normal tissue controls [PMC9680297]. FGF14-IT1 was observed to interact with the RP11-549B18.1 transcript [PMC9680297]. Furthermore, FGF14-IT1 was downregulated along with NRG1-IT1 in OS samples, while ANKRD44-IT1 was upregulated [PMC9680297]. The expression of micropeptides encoded by NRG1-IT1, FGF14-IT1, and ANKRD44-IT were highlighted by CNIT scores [PMC9680297]. In the context of male infertility after SARS-CoV2 infection, FGF14-IT has been suggested as a potential diagnostic marker along with other lncRNAs and miRNAs [PMC8231607]. Finally, in lung adenocarcinoma (LUAD), FGF14- ITI exhibited significant downregulation and was selected for further expression verification studies [PMC8358405].

Genome locations

Gene Ontology annotations

Sequence

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GUUGCUAUGGAAACCAUGGCGGCCGGAAGCCGCCGCGCGGGAGAGACUUGGGGCGCGGGUCGGGGCUAGGGCUCCUGCCCUGGCAGAGAUCUUCGCUCUUCCGUGGUGGCCGGGGACCGGGCAGUGAGCGGCCGGCUCUGCCGCCCGCGGGGCGCGGGUUUGCAAGGUGUGGCAACUCCUUCCCAGUGGAGGAAGCGACUGUUCCAAGAGCCAGUUUUGGAAUUGUAGGCACAAACACAGGAGAAUGUGGUCAGUGUUUCAGCCAGUGCUUGCUGCUGAGGCAGGAGAGAAUAAUUGUGUAAAGAGGGGGCUCCCGCAGUGCAGGACAGGAAGCCACCAUGUGAGCACCACAUCCACGUGCAGGUCGCAGGCUUCAUCAUGUCCUGAAUACCAUGCCUUAGCAUUUUAUAUUUCAGGUUUCUACUUCUACAUCUCCAGCCCUGAAUACUCAUGGAAUAUCGCUGUACCUAUGACAGGUUGCAUGAUUUUUCCCCCUCUGUGCACUCAAUUUGUGUAUUAUUGUAUCAUAUGACAUUCUGAAUCAAGUGCUGCUAGUACCAAGCUGCUAUCAUCAGCUGAUGCCAAAAAUAUUCGUUAUAACACUUCUCAGCAUGCAAGUGAGAGCACUUCAAAUCACACAGACAGAAUUUCCAGCCAUUGUUCUUUUCUUCUUUGCUUAUUAUACAGCAACAAGAAUCAAAACAAAAGGGGAUUUAUUAGAAAAUAAUGCUUCAGUAAAAUGUUAUAAAACAUGAGGUUUAUUGUUUGUGAAGAUAGAGUGAAAUUCAGUACCACAUUAUAGAUACCACCUCAGAGGCCUAUUUUCCCCUUCUUUUCUCUUUUCUCAAAUGUUUUUCAAGUGGCAUCUUUUUUUCAGUCUUUGAUUACAUUAAGGUGCAAACUAUUUAUCCAUCUGGAAAUAAGCAAUACUGUCAACAGAGAACCAGGAAAUGAAAAGUGCAGCCGGCCAUAUGCCUUCUCUACGGCCUCUUUAUGUUACUGUGCUGAUCAGGACAAAUGCAGUACCUAUGGUAGCAAUAGGGAGAGUGAAAAUAUGUAUUCUCCAAGGGAAGACAAUUAAAAGACAAAUUCCAUCAGGAAGAUUUGUCAUUUUUUGAGAGUGCUGAUCCUGCAUCUAUCAGCAAAUUUCACAUAAAUUAAUUCAUUUUACAGAGUGAAUGCUGAAACUUGGAAGCCAACUGACAAGAUGCCAGGGAUGGCAUGGCAAGGAAGAGAGAGCCUUCAUGGCAAUUUUGAAUACCUGAUCUCUUGCUUUCAUCAUCUUGUCUAGGGGAAGAAACACGGAGCCUGGUAGUUGGGAGGUGAGAGGCAGGAAUGGAUACCAGAGAUGGACAGACAGUGGGGUGGUGAGAAGGGAGCUGCAAUUUGCUAAUCCUUGUAGUACUACCUGUCAAUCAUCUUGCUUUCCUUAAUCAUCGAUCCUGGAGAGACUUUGAGGAAAGGGCUGGUGGAGUUGCGCAGAUGUGAUCUUCAUUUCAGCCUUAUGAAUACAUACCAAGGUCUCUUUAAAUCUGUGGUUCCUGCACAAAGUGCUGUGACUUCAGGCUAAUAGAGAGGUCCAGAUGUCACAUGUGCCAAUUAGAAAGAAAUGAGGACCAUGGCUAUGGCCCACUGUGUUCAGAAGACACGCCCAAGCCACCCAUUGUCAUUCAUUGUGUCUAAUACUUGACCUGUCCUGCUGUUUAUUAUGUGGGGUGGCUCCAUAUUUUAAAAACUGUAUUCAUAAAAAGAUAUUUCUCAUCCUGCUGAGUCUCAGGCCCAUUGUUGUAGGUGAGGUGGUUUCUUUUGUUUGAUAUAUAACGUUUUGCUGACUUUCGACUUGGGAAUUGCAAAGGCUUACCCAAAACCCUGAAGGAAAAGCUAAGAAUUCAUACUUAUUAAGCACUUGGUAGGUGUCUGACACUGUAGUAGAUAUAUGCGAGAGCCCAGAACAAGCUGAUGUCCAUGUACAUAUCUUUAAAAAAUAUAAUGAUCUAGUCUUAUCUGUGGAAACUGCUUCAGAUACUGAUCUUACUCUUUCCUGUUACAUCAGAAAUUCUGGAAGGUAAUAUCCUGAAAGAUUUAUCCUCAAGAAUAACAAUACAUUAAAAUCUUCUGCUUUGAAAAUGC

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Publications