hsa-mir-4252: Hsa-mir-4252 is a microRNA that is predicted to have a loss of miRNA-binding sites in a specific long non-coding RNA (lncRNA) due to the genetic variant rs10414043 [PMC8287568]. However, the expression of hsa-mir-4252 and other miRNAs could not be properly assayed, potentially leading to missed expression quantitative trait loci (eQTLs) for miRNAs that are expressed in different cell types [PMC9111935]. Further investigation into other immune cells and B-cell subsets may provide deeper insights into the impact of genetic risk variants [PMC9111935]. Hsa-mir-4252 is also associated with autophagy, as it targets autophagy-related genes such as MAP1LC3C [PMC8589263]. In patients with obesity, hsa-mir-4252 is downregulated and regulates the expression of several genes associated with obesity [PMC6102639]. Increased expression of MAP1LC3C (hsa-mir-4252) indicates autophagosome accumulation, but its absence in differential expression at baseline may be related to autophagosome clearance [PMC9781133]. In gene-miRNA interactions, hsa-mir-4252 is one of several microRNAs identified as regulatory genes [PMC10141791].