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hsa-mir-3666: Hsa-mir-3666 is a microRNA that has been identified as a tumor suppressor [PMC8965134]. In a study, it was found that hsa-mir-3666, along with hsa-miR-130a-3p, hsa-miR-130b-3p, hsa-miR-519b-3p, and hsa-miR-519a-3p, exhibited tumor suppressor activity [PMC8965134]. Another analysis revealed that hsa-mir-3666 and hsa-miR-130b-3p downregulated the expression of CEP55 and DYNLL2 genes [PMC7844508]. Additionally, hsa-miR-15b-5p and hsa-miR6838–5p downregulated CEP55 and PPP2R1B genes, while hsa-miR195–5p downregulated PPP2R1B and DYNLL2 genes [PMC7844508]. In miRWALK analysis, it was found that 16 miRNAs including hsa-mir3666 were associated with the upregulation of 8 genes [PMC9478394]. HSA-MIR3666 has been assigned the name pred-MIR222 in miRNA database miRBase [PMC2886071]. In a ceRNA network study, HSA-MIR3666 was identified as one of the miRNAs involved along with other lncRNAs and mRNAs in regulating gene expression in cancer cells [PMC9399504].
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