v24

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Homo sapiens (human) long intergenic non-protein coding RNA 1118 (LINC01118) URS000075B300_9606

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LINC01118: LINC01118 is a long non-coding RNA (lncRNA) that has been implicated in the regulation of apoptosis in epithelial ovarian cancer (EOC) cells [PMC6292151]. In a study comparing the expression of lncRNAs between chemoresistant EOC cells (SKOV3-TR30) and non-resistant EOC cells (SKOV3), it was found that LINC01118 was significantly overexpressed in the chemoresistant cells [PMC6292151]. The study focused on analyzing the early apoptosis rate of a specific zone, known as the Q4 zone, and found that LINC01118 played a role in regulating apoptosis in EOC [PMC6292151]. The aberrant expression of LINC01118, along with other lncRNAs, suggests its potential involvement in chemoresistance mechanisms and its potential as a therapeutic target for EOC [PMC6292151]. Further research is needed to fully understand the molecular mechanisms by which LINC01118 influences apoptosis and chemoresistance in EOC cells.

Genome locations

Gene Ontology annotations

Sequence

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AGGUAAAUAUUCCUCACGCCAGCAGGUGAGGAGGCUGGGGCCAGAUGACAGCUAGUGAGGGAGCAGAGACAAGACAAGGCGAGCCUGUGACAGAGCGAGACCCUGUCUCAAAAAACAAAAACAAGACAUGUGAGCUUGGACUCCAGUGUGGAAUCCCAUGUCCGCUCAGUGCACCUUUCUGCCGCUGAAAGUACAAGAGGAGAGGGGAAACCCACAGGUGGAGCUGACCAUGAGGACUGUCACAGCUUUGAGAGGCAAAUCCAGAAAUCAGCCCUCCAGCUUCCUCUACCAAGAAGACUGGCGGUUACAACCCUGGCUCUGUGGGGCUUCUCUUGCCCUCUCUUCUGACUGCCCUACUUGGCUCCAGGUGAGGGUGAGAGGAAGCUGGAGAUGGAAGAUGCAGCUGGGGGAACUCACCAGGCAGGUCUCAGGGAACUCUUUGAAUAAGAGGACACCAGAUCAUGCCUGCAGUUCCAGCCCAGGAGCAACUAGCACCAGCCUCAGCAUGGAGCAGGACUUCAGUUCCAGCAGCGAGGACUGAGAUCAGACACAAGAGAAAGCUCCCUGAUGAGGAGGGGUGAUUCUAAAACGAAGGGCGGAAAUUAUCUGGGGAAUUUCCUUCCCGUGAAGCCUCAGGAACAUGCCAGUCCCCCACUUCGGUCUGUCCUGGGGGGUCUCACGCCCCUGUCCUCCUAGAGAAAUCUAGAUCCUCCAAACUCUGCCUGGGUUCUUCCUGGGGAGUCUUGACCCCUGCCUUGUGGUUGAUGUGGGAUAGGGGACCCGGGAACAGGGCUGCCUUCCUCUGGCCAAGGCCUGGCAAGCAAGUGUGGGAUGGGUGCUGUCUUCCUGAGAGGGACAAUAGAAGUGACAGAGCCCCCUAAUUCAAGACCCUGCAGAGGUGGUGUGAGAUCUUAUAAUAUCAGUCUCUAAGCCAGUGCCUCUCAAGCUCUCUUUGGUGAAGAAUCAAUUUUUAAAAUAUAUAAUCAGUCACAGAUCAAUGCUUUUGUAAAAUGCAAUAAAAGUUAAUUUCCAAAAAAAUCACAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications