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MIR4779: MIR4779 is a microRNA that directly targets PAK2 expression, along with other microRNAs such as miR-7-5p and miR455-3p [PMC10017488]. A study analyzing the regulation of target genes for four overexpressed microRNAs in NR (MIR4278, MIR4422, MIR4779, MIR1268B) found a total of 411 interactions [PMC8138064]. Among these interactions, 16 genes were identified to be potentially regulated by MIR4278, MIR4422, and MIR4779 [PMC8138064]. Additionally, four microRNAs (MIR4278, MIR4422, MIR4779, and MIR1268B) and one snoRNA (SNORA12) with aberrant expression associated with cancer pathogenesis were identified [PMC8138064]. The tumor suppressor role of the miRNAs MIR4278, MIR4422, and MIR4779 has been reported in inducing apoptosis and cell cycle arrest as well as overall cancer survival [PMC8138064]. Furthermore, seven miRNAs (miR1297, miR4465, miR26a/b. miR4779. miR4778. miR345. and miR203) were found to be expressed at low levels in tumor tissues or cells [PMC7797122].
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Gene Ontology annotations
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