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hsa-mir-4487: Hsa-mir-4487 is a microRNA that has been studied in various contexts. It has been found to be upregulated in patients with obesity, as well as in obesity-related ccRCC (clear cell renal cell carcinoma) [PMC6102639] [PMC8490801]. In one study, hsa-mir-4487 was among the miRNAs that exhibited the greatest fold change, along with hsa-mir-4430 (upregulated) and hsa-miR-5191 and hsa-miR-3131 (downregulated) [PMC4049696]. Another study identified hsa-mir-4487 as one of the miRNAs that regulated downregulated genes in patients with obesity [PMC6102639]. In the context of ccRCC, hsa-mir-4487 was found to be among the differentially expressed miRNAs associated with obesity-related ccRCC and showed consistent upregulation [PMC8490801]. Additionally, hsa-mir-4487 was selected as one of the miRNA signatures used to build a risk-score prediction model for a specific condition [PMC8633443]. Furthermore, it has been identified as one of several miRNAs that can regulate coDEGs (co-differentially expressed genes) related to diastolic function [PMC9792148]. Overall, these studies highlight the potential importance of hsa-mir-4487 in various biological processes and disease contexts.
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