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hsa-mir-5003: Hsa-mir-5003 is one of the five miRNAs that were screened and used to develop a miRNA prognostic model [PMC5912208]. While the function of hsa-mir-139 as a tumor suppressor in various types of cancer has been extensively studied, there is a lack of relevant reports on the function of hsa-mir-5003 in cell proliferation and migration [PMC5912208]. The risk score formula for the prognostic model includes the expression levels of hsa-mir-139, hsa-mir-101-2, hsa-mir-105-2, hsa-mir-9-3, and hsa-mir-5003 [PMC5912208]. These five miRNAs were used to construct a prognostic signature based on their expression levels [PMC5912208]. Functional assessment of the target genes for hsa-mir-139 and hsa-mir-5003 suggests that these genes are significantly involved in regulating cell-based biological processes such as cell proliferation and migration [PMC5912208]. However, only the target genes for hsa-mir-139 and hsa-mir-5003 were used for further enrichment analysis due to unavailability of target gene information for other miRNAs in the Targetscan database [PMC5912208].
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