ssc-miR-1249: Ssc-mir-1249 is a microRNA that has been identified in several studies [PMC9622794][PMC7490888][PMC7222767]. It is found to be shared among different groups in a Venn diagram analysis [PMC9622794]. In one study, ssc-mir-1249, along with ssc-miR-1307 and ssc-miR-1343, showed significant up-regulation in the LL group compared to the LH group [PMC7490888]. The high expression of lncRNAs TCONS_00429684 and TCONS_00309450 in the LH group may be promoted by the absorption of ssc-mir-1249, which could lead to increased GRIK4 transcription [PMC7490888]. However, the increased expression of ssc-mir-1249 in the LL group may inhibit GRIK4 transcription and negatively impact pig fertility [PMC7490888]. Ssc-mir-1249 is also found to be involved in regulatory networks with other miRNAs and circRNAs. It may directly target circRNAs to regulate their expression [PMC7222767]. In one study, ssc-mir-1249 was highly expressed in the LL group according to both RNA-seq and RT-qPCR results [PMC7222767]. CircRNA_010551 had multiple interactions with miRNAs including ssc-miR-1343, ssc-miR-652, ssc-mir-1249, and ssc-miR-1307 [PMC7222767]. CircRNA_006954 and circRNA_006665 contained binding sites for sccmimr 1249 and were downregulated in the LL group [PMC7222767]. Overall, these studies highlight the involvement of sccmimr 1249 in various regulatory networks and its potential impact on gene expression and fertility in pigs.