dre-mir-101a: dre-mir-101a is a highly expressed miRNA in different levels of hypoxia stress [PMC8696637]. It is also found to be accumulated in the heart, along with dre-miR-130b, dre-miR-130c, dre-miR-221, and dre-miR-499 [PMC2684549]. Previous studies using in situ and Northern blot techniques have confirmed the enrichment of these miRNAs in the heart [PMC2684549]. In zebrafish, dre-mir-101a is involved in regulating genes associated with epithelial-to-mesenchymal transition (EMT) and cell cycle progression [PMC7756072]. It is also found to be anticorrelated with genes enriched for E2F targets and G2M checkpoint hallmarks [PMC7756072]. In zebrafish, dre-mir-101a specifically regulates the EMT hallmark in Cluster 5 [PMC7756072]. Additionally, miRNAs such as dre-miR-143, dre-miR-202-5p, and dre-let7c5p are associated with gonad development in Trachinotus ovatus [Wang F. et al., 2019]. In common carp (Cyprinus carpio) exposed to atrazine, ccrmiR24, ccrmiR146a, ccrmiR192, ccrmiR21, ccrmiR143 and ccrmiRNA454b are involved in regulating gonad development [Wang F. et al., 2019]. Furthermore miRNA26a/cyp19a1a regulates a feedback loop involved in protogynous hermaphroditic fish Epinephelus coioides[PMC8375321].