Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
ame-mir-1: Ame-mir-1 is a microRNA that has been shown to affect host and fungal pathogen interactions by regulating host proliferation, apoptosis, and immune response [PMC7785045]. It is speculated that the miR-1 family, which includes ame-mir-1, plays a role in the honeybee response to N. ceranae invasion [PMC6780218]. A study found a significant down-regulation of ame-mir-1 in Apis mellifera workers at 6 dpi with N. ceranae [PMC6780218]. Tests on candidate miRNAs showed similar transcription levels for both RNA strands of ame-mir-1 [PMC2394756]. Ame-mir-1 is located near ame-mir-133 and both may have similar functions in honey bees [PMC2394756]. In the larval gut of honey bees, 35 differentially expressed long non-coding RNAs (DElncRNAs) were found to target miR-1-z (highly homologous to ame-mir-1), which in turn targeted 32 differentially expressed mRNAs (DEmRNAs) [PMC9800914]. A comparison of hairpin structures showed similarities between bmo-miR-1, aga-miR-1, ame-mir-1, dme-miR-1, and dps-miR precursors [PMC2435238]. These findings highlight the importance of ame-mir-1 in regulating various biological processes in honey bees and its potential role in host-pathogen interactions.
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset