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hsa-mir-452: Hsa-mir-452 is specifically downregulated by shPIAS2_49 transfection and targets genes ST8SIA2 and ZNF532 [PMC5158200]. In endometrial cancer (EC) tissues, hsa-mir-452 is one of the significantly upregulated miRNAs [PMC3678876]. In a study on acute myeloid leukemia (AML) patients, hsa-mir-452 was identified as a protective factor for survival time [PMC5634225]. Hsa-mir-452 was found to be significantly downregulated in adipose tissue compared to normal tissue [PMC8986441]. Hsa-mir-452, along with hsa-mir-29a, hsa-mir-29b, and hsa-mir-29c, synergistically regulated the gene NAV3 [PMC3878884]. The function of hsa-miR-371-3p and hsa-mir-452 in hypertrophic cardiomyopathy (HCM) has not been clarified yet, but they share the same targets as hsa-miR-373 [PMC8200816]. Hsa-mir-4713 and hsa-mir-452 were found to interact with NPY1R [PMC8986441]. The lentivirus vector for introducing hsa-miR-452 was purchased from GeneCopoeia for experimental purposes [PMC5596211].
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