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bta-miR-181b: Bta-mir-181b is a miRNA that is significantly upregulated in cows with mastitis compared to healthy cows [PMC6107498]. It is one of the 123 mastitis-related miRNAs that experience upregulation in mastitis [PMC6107498]. Bta-mir-181b is also found to be a target of the novel_circ_0006981 [PMC7230347]. It is encoded in an intergenic region of the Bos taurus genome [PMC5384155]. Bta-mir-181b, along with other differentially regulated miRNAs, has been associated with cellular proliferation or apoptosis [PMC5384155]. It is located on chromosome #16 along with bta-miR-34a and bta-miR-205 [PMC5384155]. The ViTa algorithm suggests that bta-mir-181b could potentially target the genome [PMC5384155]. Bta-mir-181b, along with other miRNAs, has been found to be clustered in this study [PMC5384155]. In serum from persistently infected cattle, bta-mir-181b was significantly down-regulated compared to healthy cattle [PMC5384155]. Bta-mir-181b has been associated with immune modulatory functions along with other miRNAs such as bta-miR-26b and bta-miR-34a [PMC5384155]. Bta-miR-181a, which belongs to the same family as bta-mir-181b, has been reported to regulate milk lipid synthesis by targeting ACSL1 enzyme in bovine milk biosynthesis [PMC6637853].
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