Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
ssc-miR-181b: Ssc-mir-181b is a differentially expressed (DE) miRNA that was evaluated in a study [PMC7531090]. It was one of three DE miRNAs, along with ssc-mir-423-5p and ssc-mir-196b-5p, that were analyzed in the study [PMC7531090]. Additionally, ssc-mir-181b was one of eight DE miRNAs selected from a larger group of 45 miRNAs [PMC7531090]. The study also investigated the target sequences of ssc-mir-181b and other miRNAs using the pMIR-REPORT Luciferase vector [PMC5776175]. The expression levels of ssc-mir-181b were measured using qRT-PCR on the StepOnePlus RT-PCR System [PMC7383124]. Interestingly, another study found low and unchanged expression levels of ssc-mir-181b in colorectal cancer (CRC) development in humans [PMC5707088]. Although these differences did not reach statistical significance, they were consistent with data from small RNA sequencing [PMC5707088]. Finally, qRT-PCR validation confirmed the differential expression of ssc-mir-181b along with other miRNAs including ssc-miR-155-5p and ssc-miR191 in CRC development [PMC5707088].
References:
[PMC7531090] - This reference is for the evaluation and selection of DE miRNAs.
[PMC5776175] - This reference is for the investigation of target sequences using pMIRREPORT Luciferase vector.
[PMC7383124] - This reference is for measuring expression levels using qRTPCR on StepOnePlus RTPCR System.
[PMC5707088] - This reference is for low and unchanged expression levels in CRC development.
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset