hsa-mir-4508: Hsa-mir-4508 is a specific miRNA that is downregulated in the comparison of ART vs HIV- [PMC4865051]. It is also one of the five most exosomal enriched miRNAs in exosomes, along with hsa-miR-1246, hsa-miR-4488, hsa-miR-4492, and hsa-miR-4516 [PMC6306394]. Hsa-mir-4508 has been found to have 18 targets, including solute carrier family 43, member 3 (SLC43A3) and solute carrier family 12 (potassium/chloride transporter), member 4 (SLC12A4), which are involved in the regulation of prolactin levels in the amniotic fluid and fetal development [PMC9601722]. In a study comparing treated cells with untreated cells, hsa-mir-4508 was found to be significantly upregulated along with other miRNAs such as hsa-miR-4488 [PMC8851033]. Furthermore, targets have been identified for hsa-mir-378e (310 targets), hsa-miR-708-3p (457 targets), and hsa-mir-4508 (125 targets) [PMC9601722]. Overall, these findings highlight the role of hsa-mir-4508 in various biological processes and its potential as a therapeutic target.
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