ssc-mir-129b: ssc-mir-129b, a microRNA, was among the four miRNAs validated by qRT-PCR to assess expression differences in RNA-Seq studies [PMC8834144]. It was identified as one of the most affected RNAs in a network analysis involving miRNA and mRNA interactions [PMC8861501]. Although ssc-mir-129b showed better trends in expression upon ZEN exposure, it was one of the microRNAs down-regulated, suggesting a potential role in the response to this mycotoxin [PMC6598998], [PMC6722729]. However, its low expression levels indicated a minimal impact on immunity or inflammation in porcine peripheral blood mononuclear cells (PBMCs) [PMC7903524]. Upon lipopolysaccharide (LPS) stimulation, ssc-mir-129b was significantly up-regulated alongside other miRNAs, suggesting its involvement in inflammatory responses and warranting further investigation into its potential functions and target genes within porcine PBMCs [PMC7903524]. Despite its low abundance (<10 TPM), ssc-mir-129b's up-regulation upon LPS stimulation highlights its possible regulatory role under inflammatory conditions [PMC7903524].