hsa-miR-3648: Hsa-mir-3648 is a dysregulated miRNA that has been studied in various diseases, including chronic hepatitis C (CHC) and colorectal cancer (CRC). In CHC, dysregulated miRNAs, except for hsa-mir-3648 and hsa-miR-1908-3p, were disrupted in individuals with an HCV+ infection, indicating a similar miRNA-mediated posttranscriptional regulation [PMC6617112]. In CRC, hsa-mir-3648 is one of the miRNAs that show continuously increasing expression with CRC progression [PMC9304430]. Hsa-mir-3648 has also been identified as one of the top differentially expressed miRNAs in various cancer types, including breast carcinoma [PMC4696739], bladder cancer [PMC9845264], and small cell lung cancer (SCLC) [PMC5929426]. Additionally, hsa-mir-3648 has been found to have human-specific substitutions and is also disrupted in the chimpanzee lineage [PMC4966751]. However, it should be noted that hsa-mir-3648 does not have predicted target genes according to a specific tool used for analysis [PMC3548844]. Overall, hsa-mir-3648 has been implicated in various diseases and shows differential expression patterns that may have diagnostic or prognostic significance.