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SNORA72: SNORA72 is a small nucleolar RNA (snoRNA) that has been found to play a role in inducing the stemness of ovarian cancer [PMC7669759]. It does so by activating the Notch1/c-Myc pathway [PMC7669759]. Specific primer sequences for SNORA72 were designed by RiboBio in Guangzhou, China, and small nuclear RNA U6 was used as the internal control [PMC7669759]. These findings highlight the potential significance of SNORA72 in ovarian cancer and provide insights into its mechanism of action. The activation of the Notch1/c-Myc pathway by SNORA72 suggests that it may contribute to the self-renewal and proliferation of cancer stem cells, which are known to play a crucial role in tumor progression and therapy resistance [PMC7669759]. The use of specific primer sequences for SNORA72 allows for its detection and quantification, which is important for studying its expression levels in ovarian cancer cells and tissues. Additionally, the use of small nuclear RNA U6 as an internal control ensures accurate normalization of SNORA72 expression levels [PMC7669759]. These findings contribute to our understanding of the molecular mechanisms underlying ovarian cancer stemness and provide potential targets for therapeutic interventions.
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