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hsa-miR-1972: Hsa-mir-1972 is a microRNA that has been found to target BAIAP3 and inhibit its expression in vitro [PMC7906144]. In a study comparing CVID patients at two time points, hsa-mir-1972 was one of the microRNAs that showed significant expression differences [PMC7722869]. Hsa-mir-1972 is also involved in the regulation of THSD4, a down-regulated mRNA, through its interaction with other microRNAs [PMC8799076]. Although hsa-mir-1972 was predicted by multiple databases, it was found to have a miRNA-target interaction with only one gene, TCF3 [PMC5994059]. In the context of LA pathogenesis, hsa-mir-1972 displayed the most significant change in expression and was associated with up-regulated mRNAs in WML tissue [PMC7906144]. Additionally, hsa-mir-1972 showed lower expression levels in plasma of patients with type I LA compared to subjects without LA [PMC7906144]. In patients with AS compared to normal controls, hsa-mir-1972 was found to be downregulated along with other miRNAs [PMC7795580]. These findings suggest that miRNAs like hsa-mir-1972 have potential as biomarkers for disease progression and understanding disease targets and factors [PMC7795580].
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