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cfa-mir-30d: Cfa-mir-30d is a microRNA that has been found to be significantly downregulated in dogs with stage C and D heart diseases compared to healthy controls [PMC9607079]. In a study investigating serum levels of 11 candidate miRNAs associated with cardiac hypertrophy in dogs, cfa-mir-30d was one of the miRNAs investigated [PMC8542680]. It was found to be upregulated in the PDA group of dogs [PMC8542680]. Cfa-mir-30d is also one of the miRNAs with the highest activity in the adrenal cortex and pituitary of dogs, along with cfa-miR-30a, cfa-miR-7, cfa-miR-7g, cfa-miR-125a, and cfa-miR-125b [PMC4768678]. In adrenal cortex samples, cfa-mir-30d is part of the miRNA family that includes cfa-miR-30a, cfa-miR-30b, and cfa-miR-30c [PMC4768678]. In pituitary samples, it is part of the miRNA family that includes cfa-miR-30a and cfa-mir-30d [PMC4768678]. Finally, in dogs with mitral valve disease (MMVD), it was found to be significantly downregulated compared to healthy dogs [PMC8062772].
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