ssc-miR-124a: ssc-mir-124a is a specific type of microRNA that has been found to target the NP genes isolated in all 38 different times [PMC5412334]. It has also been observed that the interaction of ssc-mir-124a and NP was not predicted in a particular study, possibly due to different prediction tools and criteria, or the sequence-specificity of SIV-H1N1/2009 [PMC5412334]. The putative interactions of ssc-mir-124a with its SIV target genes have been found to be maintained throughout virus evolution [PMC2828889]. Additionally, ssc-mir-124a has been shown to regulate the inflammatory response by downregulating IL-1 expression during chronic T. gondii infection [PMC8851844]. It has also been associated with the inactivation of the Notch signaling pathway by potentially targeting TNIP2 and RPS6KA4 [PMC8851844]. Furthermore, ssc-mir-124a expression is decreased during PRRSV infection, leading to the downregulation of CD163 mRNA and protein levels by targeting CD163 mRNA sequence [PMC9522899]. Additionally, ssc-mir-124a has been found to be upregulated in exosomes and is involved in upregulating important signaling molecules such as p-AKT and p-ERK1/2 [PMC8814829]. It is specifically expressed in ER and participates in immune-related pathways along with other miRNAs such as ssc-miR-10b and ssc-miR-128 [PMC6677090] [PMC10000162]. Epigenetic upregulation of ssc-mir-124a has also been shown to attenuate apoptosis and inflammation during CPB2 toxin infection [PMC9253665].