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rno-mir-182: Rno-mir-182 is a microRNA that is upregulated in various biological processes, including myocardial remodeling [PMC5819922]. It has been found to target members of the DNAJ heat shock protein family (Hsp40) [PMC6377737]. The sequence of rno-mir-182 is 5′-ACGCGGGUCUAGCUGCCGGAGGCCUCCCACCGUUUUUGGCAAUGGUAGAACUCACACCGGUA-3′ [PMC5133994]. It has been used in experiments involving transfection to rat neonatal cardiomyocytes and Hela cells [PMC5133994]. In the hippocampus, rno-mir-182 has been predicted to target a total of 475 genes [PMC5832017]. TaqMan miRNA assays have been used to study rno-mir-182 expression levels [PMC6255182]. In different studies, rno-mir-182 has been found to be differentially expressed in various tissues and conditions, including VSMCs exposed to high glucose levels, rat cortex during neurogenesis, and liver tissues in a model group compared with a control group [PMC7248521] [PMC3441217] [PMC6102666]. It has also been associated with the regulation of thecal hyperandrogenesis and target genes such as CTTN have been experimentally confirmed for rno-mir-182 regulation in other diseases [PMC3682887] [PMC4601749].
mRNA interactions
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