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hsa-mir-548k: Hsa-mir-548k is a microRNA that has been identified as one component of a seven-miRNA panel [PMC8582539]. It has been found to have higher expression in 3p arm loss, which is associated with poorer overall survival [PMC8582539]. Studies have shown that hsa-mir-548k enhances malignant phenotypes and tumor progression in esophageal cancer [PMC8582539]. It has also been identified as one of the differentially expressed miRNAs in the intersection of DEG targets [PMC8503613]. In sepsis, hsa-mir-548k has been found to potentially regulate prognosis, along with other lncRNAs and miRNAs [PMC9976425]. Hsa-mir-548k expression has been observed to be higher in cellular samples compared to FF samples [PMC8501715]. Lentiviruses for overexpression and inhibition of hsa-mir-548k have been used in experiments [PMC6775607]. Hsa-mir-548k has also been validated as being in the same direction of effect in different studies [PMC8073146]. It is one of the miRNAs used to calculate a risk score for cancer prognosis prediction, along with other clinical features [PMC8176021]. Hsa-mir-548k has also been found to target several pRS-related mRNAs and is associated with satisfactory K-M curves performance [PMC8176413]. In HPV-negative groups, hsa-miR-135b-3p, hsa-miR-605-5p, hsa-miR-383-5p, hsa-miR518a5p, hsa-miR1911 5p and hsa mir 548k were used for risk score calculation.
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