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mmu-mir-183: Mmu-mir-183 is a microRNA that has been studied in various contexts. In one study, alcohol treatment was found to down-regulate mmu-mir-183, along with other miRNAs such as mmu-mir-143 and mmu-mir-96, while up-regulating miRNAs like mmu-mir-351, mmu-mir-150, and mmu-mir-125b [PMC6206094]. Another study found that the collection of transcripts within the miRNA signature set correlated significantly with mmu-miR-193 but differed from the collection of transcripts within the miRNA signature set of the mmu-miR-128 and mmu-mir-183 families [PMC3130556]. In a study comparing young and old mice, it was observed that mmu-miR-695, mmu-miR-31, and other miRNAs were significantly downregulated in old mice compared to young mice [PMC3742134]. The expression of these miRNAs was validated using qRT-PCR analysis [PMC3742134]. Mmu-mir-183 expression has also been studied in medulloblastomas. In one study, it was found that the expression of mmu-mir -183 increased in Ptch1+/-;PtenFloxp/+ GFAP-Cre medulloblastoma compared to Ptch1+/- medulloblastoma [PMC3841474]. Additionally, specific miRNAs like mmu-mir -182 and other members were found to be regulated by a core set of transcription factors including Oct4, Sox2, Nanog, and Esrrb [PMC9149258]. Finally, Hmgcs2 was identified as a potential target regulated by several microRNAs including mmu -mir -183 [PMC3692539].
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