ssc-mir-130a: Ssc-mir-130a is a microRNA that has been found to be significantly associated with palmitic acid content, saturated fatty acid (SFA) and unsaturated fatty acid (UFA) proportion, and backfat thickness in the GM muscle [PMC8097994]. It has also been associated with negative regulation of DDX58/IFIH1 signaling of type I interferon response and p53 signaling pathways [PMC8097994]. There are differences in the genomic DNA sequences of ssc-mir-130a between Sscrofa 10.2 and mmu-miR-130a precursor [PMC5776175]. Ssc-mir-130a is predicted to target the MAPK1 gene, along with other microRNAs [PMC3901342]. It has been shown to target the PPARγ gene in pigs, similar to its function in humans and mice [PMC4959853]. Ssc-mir-130a is mainly expressed in the lungs and is one of several miRNAs expressed in different pig tissues [PMC3427155]. In a study on E. coli F18-susceptible pigs, ssc-mir-130a was found to be upregulated and regulated by three different transcription factors [PMC3427155]. References: [PMC8097994] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097994/ [PMC5776175] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776175/ [PMC3901342] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901342/ [PMC4959853] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959853/ [PMC3427155] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427155/