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hsa-mir-545: Hsa-mir-545 is a microRNA that has been studied in various contexts. In a study on breast cancer prognosis, hsa-mir-545 was found to be significantly up-regulated in breast cancer tissues compared to normal tissues [PMC8004706]. Another study on myocardial infarction found that hsa-mir-545 downregulates the expression of SLC7A2 mRNA [PMC7764698]. In ovarian cancer, hsa-mir-545 was found to be predominantly expressed in patients with wild-type BRCA1/2 ovarian cancers who may benefit from platinum-based chemotherapy [PMC4522283]. Additionally, hsa-mir-545 was identified as one of the four candidate microRNAs that target the IL12B 3′UTR sequence, which is located proximally to A+1188C [PMC3470565]. Furthermore, a risk score calculation using multiple miRNAs including hsa-mir-545 showed promising results in predicting prognosis in breast cancer patients [PMC8176021]. Overall, these studies highlight the potential role of hsa-mir-545 as a biomarker and therapeutic target in various diseases.
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