hsa-mir-3175: Hsa-mir-3175 is identified as one of the three significant DEmiRNAs that regulate HDAC7, along with hsa-miR-23a-3p and hsa-miR-23b-3p, and it plays a regulatory role in the progression of systemic inflammatory cardiomyopathy (SIC) by interfering with HDAC7/ACTN4 in monocytes and cardiac tissue cells [PMC9218607]. Hsa-mir-3175, along with hsa-miR-23a-3p and hsa-miR-23b-3p, is hypothesized to regulate SIC progression by influencing the inflammatory response and apoptosis through the translation of HDAC7 [PMC9218607]. Hsa-mir-3175 is a human-specific miRNA that shows a 100% sequence identity between known mature mouse, human, rat, and Chinese hamster miRNAs [PMC4139590]. It is not found in the genome of CHO-K1 (Chinese hamster ovary) cells [PMC4139590]. Hsa-mir-3175 is one of the DEmiRNAs that regulate THSD4, a down-regulated DEmRNA in prostate cancer (PCa), along with hsa-miR107 and hsa-miR484 [PMC8799076]. It has been suggested that THSD4 might be a potential regulator of PCa through its regulation by these PCa-related miRNAs [PMC8799076]. Additionally, hsa-mir-3175 can regulate various target genes associated with immune response and angiogenesis leading to placental insufficiency [PMC8779150].