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rno-mir-137: Rno-mir-137 is a microRNA that has been studied in the context of propofol treatment in primary cultured embryonic NSCs [PMC4171549]. The primer sequences for the amplification of rno-mir-137 were 5′-TT + ATT + GCTTAAGAATA-3′ (forward) and 5′-GTAAAACGACGGCCAGTCTACGCG-3′ (forward) [PMC4171549]. Propofol was found to regulate the expression of rno-mir-137 and its target genes, ARC and EGR2 [PMC5064799]. The expression levels of rno-mir-137 were downregulated at T1 but upregulated from T2 to T4 [PMC5064799]. Additionally, rno-miR-19a, rno-miR-19b-2, and rno-miR-214 were downregulated at all four time-points [PMC5064799]. The fold-change in the mean expression levels of rno-mir-137 ranged from -2.02 to 4.61 [PMC5064799]. These findings suggest that propofol treatment can modulate the expression of rno-mir-137 and other miRNAs in primary cultured embryonic NSCs [PMC5064799].
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