bta-mir-16a: Bta-mir-16a is a microRNA that has been identified as one of the top 13 most abundant miRNAs in all samples [PMC6600136]. It is regulated by transcription factors LEF1 and AP1 [PMC8511192]. Bta-mir-16a has also been found to be differentially expressed in response to SFO treatment and is associated with the regulation of certain traits [PMC6164576]. In the context of bovine mastitis, bta-mir-16a is one of the 123 mastitis-related miRNAs that experience significant upregulation compared to healthy cows [PMC6107498]. It has been used as an internal control to normalize the read counts of other bta-miRNAs in B cells [PMC8432782]. Additionally, bta-mir-16a has been quantified in oxidized bovine blood RNA and found to be differentially expressed between winter and summer periods [PMC9866016] [PMC9686552]. The mimics of bta-mir-16a were used in a study investigating its effect on MS [PMC7700136]. In summary, bta-mir-16a is a microRNA that plays a role in various biological processes, including mastitis, SFO treatment response, and seasonal variations. Its expression levels have been studied in different contexts and it has been found to be regulated by transcription factors. The abundance and stability of bta-mir-16a make it a valuable candidate for further research on its functional role.