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hsa-mir-192: Hsa-mir-192 is a microRNA that has been associated with nonalcoholic liver diseases [PMC7936154]. Exosomes derived from hepatocytes treated with palmitic acid showed significantly higher levels of hsa-mir-192, along with other microRNAs such as hsa-miR-24, has-miR-19b, hsa-miR-34a, and hsa-miR-122 [PMC7936154]. These microRNAs have been previously linked to nonalcoholic liver diseases [PMC7936154]. Hsa-mir-192 is one of the microRNAs that displayed the highest connectivity and regulated 25 targets [PMC5620483]. Hsa-miR-26b, hsa-mir-192, hsa-miR-21, hsa-miR-181a, and hsa-miR-155 were found to regulate 43, 25, 26, 15 and 11 targets respectively [PMC5620483]. These findings suggest that these microRNAs may play a significant role in the regulation of various cellular processes in hepatocytes. The upregulation of these specific microRNAs in exosomes derived from palmitic acid-treated hepatocytes may have implications for the development and progression of nonalcoholic liver diseases. Further research is needed to fully understand the functional significance of these findings and their potential as therapeutic targets for liver diseases.
mRNA interactions
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Genome locations
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