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hsa-mir-222: Hsa-mir-222, a microRNA, was found to be associated with poor prognosis in EBV+DLBCL patients, with a study revealing two distinct subpopulations based on its expression levels [PMC4322989]. Specifically, patients with elevated levels of hsa-mir-222 were predominantly non-GCB subtype and were determined to have the worst prognosis according to the Salles algorithm [PMC4322989]. Furthermore, a high percentage of these patients were in advanced stages of the disease (Ann Arbor stage III or IV) and had an International Prognostic Index (IPI) greater than 2, indicating a more aggressive disease course [PMC4322989]. Despite various clinical features associated with poor outcomes being prevalent in this group, only the correlation with Salles classification reached statistical significance [PMC4322989].
mRNA interactions
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