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Mus musculus (house mouse) mmu-miR-669c-5p URS00000D9C2B_10090

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mmu-mir-669c: Mmu-mir-669c is a member of the miR 297-669 cluster and is associated with the regulation of glutathione metabolism in the liver of aging mice [PMC3424575]. It is involved in glycerophospholipid metabolism and targets genes such as Dgka, Dgke, Pla2g10, Gnpat, and pla2g12a [PMC3573770]. Mmu-mir-669c is located within an intron of the Sfmbt2 gene, which interacts with the transcription factor YY1 to potentially form a PcG silencing complex [PMC2705851]. It has also been shown to be up-regulated in SP+ LCSCs after CTX treatment and may play a role in lung cancer progression [PMC5617494]. Additionally, mmu-mir-669c is associated with other transcription factors for the regulation of common targets within each regulation network [PMC4531287]. Overall, mmu-mir-669c is a microRNA involved in various biological processes and has been implicated in liver aging, glycerophospholipid metabolism, lung cancer progression, and other regulatory networks.

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