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osa-miR396f-5p: Osa-mir396f-5p is a microRNA that has been found to be differentially expressed in rice upon infection with the fungus R. solani [PMC9189367]. The expression levels of the target gene REX1 for osa-mir396f-5p were authenticated [PMC8472271]. However, the expression patterns of osa-mir396f-5p and its target gene REX1 did not show a contrasting pattern, suggesting that REX1 may not be the actual target gene of osa-mir396f-5p [PMC8472271]. Osa-mir396f-5p was also found to be differentially expressed in response to different strains of R. solani, showing upregulation against Lud-1 and downregulation against Imph-2 and Chn-1 strains [PMC7662745]. Osa-mir396f-5p was also found to be induced in both susceptible and resistant rice cultivars upon infection with R. solani, suggesting its role as a basal response regulator against the pathogen [PMC7662745]. The multifaceted host resistance mechanisms in rice were suggested by the identification of osa-mir396f-5p along with other miRNAs involved in rice immunity against M. oryzae [PMC5066168]. The differential regulation of osa-mir396f-5p among different strains of R. solani suggests its involvement in strain-specific host-pathogen interactions [PMC7662745].
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