v24

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Homo sapiens (human) long intergenic non-protein coding RNA 1931 (LINC01931) URS00000658C9_9606

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LINC01931: LINC01931, also known as MMADHC divergent transcript, is a non-coding RNA located on chromosome 2 [PMC8770724]. In a study investigating risk factors for poor survival in lung squamous cell carcinoma (LSqCC) patients, LINC01931 was identified as one of the significant risk lincRNAs [PMC6900396]. High levels of LINC01931 were found to be associated with poor prognosis and predicted a lower survival rate in LSqCC patients [PMC6900396]. In particular, the 1-year, 5-year, and 10-year survival rates were significantly higher in the LINC01931 low-level subgroup compared to the high-level subgroup [PMC6900396]. Additionally, KM curves and lifetest analysis confirmed that high levels of LINC01931 were associated with poorer overall survival in LSqCC patients [PMC6900396]. The region where LINC01931 is located (2q23.3) has also been suggested to be associated with colorectal cancer in Hispanics [PMC6900396]. It is worth noting that lincRNAs often co-express with their neighboring genes and regulate their transcription. Therefore, it is possible that LINC01031, LINC01088, and LINC01931 may promote LSqCC through their neighboring genes [PMC6900396]. These findings suggest that targeting lincRNAs such as LINC01931 may hold promise for the treatment of LSqCC patients [PMC6900396]. References: - PMC8770724 - PMC6900396

Genome locations

Gene Ontology annotations

Sequence

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GCAAUUAAUGCUGAAACACAGCUAGCAUACAUAGCAAUAACUUAGGCAAAAAGGCAACACUCAAGCAAAAUCCUUCCUGGAAUUAAAAUCCUGUUAUUAGGUCAACCAACUUUUCUUUUAACUAACUAAAUAAACAACAGCAAGACAUGAAACCUAGACCUAUAAGUUUAGUACCUGAAUCUCUUGCUGAUUCAUGCAUUUCUAUUAAUCUUCUCAGUCAGAUGUUUAGCUCAGAUCUGUCCUCUUAUCCAAGCUUUUCCAAGAGUCUCCUAGCUACACUUCUGGCAUCAUGUUACACCCUACAAUCCAGCUCUUCACAGUCUCCUGACUUCUUUUUAAAAGUUGCAUACUAUAUAUACAUCUCUCUCUUGCUUAACAUUCCUCAGUUAUUCCCUAGUGGACACAGAAUAAAGUCUAGCUUCUUAGCAUGUUACUUGGGCUCCUUCAGUGCCAGUCCCCACAAAUUCCUCACUCAUCUUGCAGAAGCUCCCAGUUUUCAAUAUUCUCCUAAAUGCUGUGGAACCUCUGUCUAUGCAGGAUUCUAAAGAUGAGGAAAAUUAGUCCCUUAAGACUCAGCUUAAGCAUUGCCCCUUGUGCCUUUACUGUUAGUUUGCCCCUCUGUUCUUAAGAGUUUAUUCCUGGCAUUGCUCUUAAGGGAAGGAAGUUUGGCAGGGCCAAGAGUCCUAAACGUUAGACCUUUCUCUCUAAACACUAACAACAUUAAAACUCCAUUCAAGAAGGAGCAAAAGAAGCCAUCAUCUAGAAACAAUGUUGAUAACCACAGUUCCUGAACUUGGGCUUGUUAAAAGACUUUAUCUCCAUGAGUAUACUGAAACACAUAUUUAGUUUAUCUCCUAUUAUCAAGAAAGAAAUAUUAAAACUUCACUGUUGAGGAUCACUCUGAAUAUGAAAGUGCUCAAGACAAUCAAUCAGGUCUCGAGAUCUAGAAAUUAGUAUAAGUACUGAGUGCUAGGGGAAAAAAAUUAUACUCUUCAAACUACAUCCCUGGGAGUGUUAGUGAUGUCAUAAUUCACUGAGGAUCUAGAAACUACAGGAUGGAUACUUAUAAAAGAUAAGGGAAGUAUAGUGCAUAGGUUGCUGAGAGGUGGAGAGAAAGUUGCUUACUUUUCCUGAGCCUCAACUUUCUGAAAACAUAGAAACACAAUUAGAUGAUGAGUUAUGAGGUGAAGGAGGGGAUGACUCAGCAGCAAUGUGCCAGCUCCAUAGUGACUUCUCCACCAAGCUGGAGAAGGAUUUGCAGCAAUGGUUCCAGAACCAACUGUGUGUAUCUACAGGAUGAAGAUCAUUUAGACUAUGAUCAUUUAGACUGUAUCACUUUUGAUUCUUUCUAUGUUGCCCAGGCUGAUCUCAGAUUCCUGGGCUGAAGUGAUCCUCCUGCUUCAGCCUCCAGAGCAGCUGGGAUUACAGCAGCUUCAGUGCUGAGGCUAAUGGCAAAGGAAACACCAGGGGAUCAGUGAGUAAGAACUUGUCAAGGGAACAAAGUCUGAAGAUGGAACGGAGGAAGAGGAGAAAAUCUUCCACCAAAAAAAAUAUUAAAAUCUGAUCUUCAAGGAAAUACUGAAUCCACAUAGCACUCCCCUCCGCUCCCUUCUUAGGCACAGCAUUACUCACCAUCUCACAGAGGAGAAACAGAAAUAUAAAAUAAAAAGUGGAAACAAUCAUUAAAAAUACUUAGCCACUCCCACGUGUCCUGGGAAACUGAGAACACAGUAACUACCAAACAAAUUACAUGAUGUCACAUGCCAGAUACCUAAAGGAUAACAUCACCCCAUCUUCAGAAACAGAAGAAAAUAAAAUAGCAAAAGCAAGAG

Taxonomic tree

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Expression New Publications