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Homo sapiens (human) hsa-miR-4775 URS000005542C_9606

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hsa-mir-4775: Hsa-mir-4775 is a microRNA that has been found to be upregulated in patients with Alport syndrome, suggesting its involvement in the disease [PMC7998154]. It has also been identified in several other studies [PMC9742375]. Hsa-mir-4775 has been shown to target the ATF2 gene, which is involved in arresting viral infection, as well as SMAD7, a protein involved in the TGF-beta signaling pathway [PMC9742375]. It has been found to be the most prominent miRNA in terms of associations with proteins and target transcripts [PMC6297794]. Hsa-mir-4775 has also been implicated in colorectal cancer invasion and metastasis [PMC6297794]. Additionally, it has been predicted to target the 3╩╣UTR of SARS-CoV-2 and play a role in modulating the immune response after infection [PMC8201247]. In relation to diabetic nephropathy, hsa-mir-4775 is associated with targeting apoptotic pathway core genes and upregulating CFB gene expression [PMC8527307]. Furthermore, hsa-mir-4775 has been shown to bind to DCP1B mRNA and its binding may be affected by genetic variations [PMC4093940]. Overall, hsa-mir-4775 appears to play a role in various diseases and biological processes.

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Gene Ontology annotations


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