rno-mir-144: Rno-mir-144 is a microRNA that has been shown to be involved in swimming exercise-induced physiological cardiac hypertrophy. This hypertrophy is related to the modulation of several miRNAs, including rno-mir-144, rno-miR-21, rno-miR-124, and rno-miR-145, which target components of the PI3K/AKT/mTOR signaling pathway [PMC5908320]. The expression of rno-mir-144 and rno-miR-451 has been observed in blood cells in an in vivo study [PMC4184830]. The bioinformatic analysis provided by MicroCosm Targets has indicated that rno-mir-144 can bind to the GRP78 mRNA 3'-UTR [PMC4184830]. The expression of rno-mir-144 and other miRNAs peaked at different time points after hCG treatment [PMC4184830]. In contrast, the expression of rno-mir-144 and rno-miR-451 decreased significantly after hCG treatment [PMC4184830]. Overexpression of rno-mir-144 has been shown to reduce myocardial injury and apoptosis in rats with ischemia-reperfusion injury [PMC7238603]. These findings suggest that rno-mir-144 plays a role in cardiac hypertrophy and can regulate GRP78 expression.