Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Rattus norvegicus (Norway rat) rno-miR-144-5p URS000004F117_10116

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

rno-mir-144: Rno-mir-144 is a microRNA that has been shown to be involved in swimming exercise-induced physiological cardiac hypertrophy. This hypertrophy is related to the modulation of several miRNAs, including rno-mir-144, rno-miR-21, rno-miR-124, and rno-miR-145, which target components of the PI3K/AKT/mTOR signaling pathway [PMC5908320]. The expression of rno-mir-144 and rno-miR-451 has been observed in blood cells in an in vivo study [PMC4184830]. The bioinformatic analysis provided by MicroCosm Targets has indicated that rno-mir-144 can bind to the GRP78 mRNA 3'-UTR [PMC4184830]. The expression of rno-mir-144 and other miRNAs peaked at different time points after hCG treatment [PMC4184830]. In contrast, the expression of rno-mir-144 and rno-miR-451 decreased significantly after hCG treatment [PMC4184830]. Overexpression of rno-mir-144 has been shown to reduce myocardial injury and apoptosis in rats with ischemia-reperfusion injury [PMC7238603]. These findings suggest that rno-mir-144 plays a role in cardiac hypertrophy and can regulate GRP78 expression.

Genome locations

Gene Ontology annotations


Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

This sequence is found in 16 other species