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SNORD51: SNORD51 is a small nucleolar RNA (snoRNA) that is involved in various biological processes [PMC6612641]. It has been found to be down-regulated with age and rapamycin treatment, along with other lncRNA neighbors of LAMTOR5 [PMC6612641]. The expression of SNORD51 has been shown to be significantly different between pCR and pIR, with downregulation in the pIR group [PMC7690383]. In hepatocellular carcinoma (HCC) tissues, SNORD51 is highly expressed, while the expression of other snoRNAs such as SNORA20, SNORD10, and SNORD14D is reduced [PMC7093170]. SNORD51 has also been identified as one of the genes that overlap with long-term-only induction in complete remission (CR) [PMC6945282]. It belongs to the C/D box snoRNAs group and plays a role in 2'-O-ribose methylation on ribosomal RNA (rRNA) [PMC7027068]. Additionally, SNORD51 has been found to have sequence complementarity with Pxdn mRNA and is involved in its 2'-O-methylation by fibrillarin [PMC7200641]. In risk models for different cohorts, SNORD51 has been included as one of the genes used for prediction [PMC9939161]. Overall, these studies highlight the diverse roles and regulatory mechanisms associated with SNORD51.
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