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Homo sapiens (human) hsa-miR-339-5p URS000003FD55_9606

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hsa-mir-339: Hsa-mir-339 is a microRNA that has been found to be up-expressed in VP and ART and down-expressed in EC and HIV- [PMC4165582]. It has been included in Taqman MicroRNA assays [PMC7697734]. The expression level of hsa-mir-339 did not change in relation to hsa-miR-221 [PMC4745707]. It has been suggested that novelMir-1 should be called a paralogue of hsa-mir-339 and labeled as hsa-mir-339_1 [PMC9580950]. The novelMir-1 has an identical seed as hsa-mir-339 but is mapped at a different genomic location [PMC9580950]. The precursor of hsa-mir-339 generates two miRNAs, miR-339-3p and miR-339-5p [PMC8799122]. In silico analysis has shown that the 3'UTR SNP is a putative microRNA binding site for hsa-mir-339, suggesting a functional role for this region of the gene related to mRNA expression of NRXN1 [PMC3110800]. Hsa-mir 339 has an almost perfect complementary miRNA/mRNA duplex with an extremely low free energy [-42,30 kcal/mol] [PMC2674674]. Hsa-miR 200a is another previously reported microRNA, but its relationship to hsa-miR 892b, hsa mir 3375p, and several other miRNAs including some from the mir30 family is not supported by evidence or references. Therefore, the claim that hsa-miR 200a is related to these miRNAs is false. However, the role of hsa-miR 200a and the other miRNAs mentioned remains unverified [PMC6497741].

mRNA interactions 4 total

Genome locations

Gene Ontology annotations


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This sequence is found in 8 other species

  1. Cavia porcellus (domestic guinea pig) cpo-miR-339-5p
  2. Cricetulus griseus (Chinese hamster) cgr-miR-339
  3. Dasypus novemcinctus (nine-banded armadillo) dno-miR-339-5p
  4. Echinops telfairi Ete-Mir-339_5p (mature (guide))
  5. Macaca mulatta (Rhesus monkey) mml-miR-339-5p
  6. Mus musculus mmu-miR-339-5p
  7. Pongo pygmaeus ppy-miR-339-5p
  8. Rattus norvegicus rno-miR-339-5p