hsa-mir-518c: Hsa-mir-518c is a microRNA that has been associated with the tumorigenesis of retinoblastomas [PMC2831057]. In a study, hsa-mir-518c was found to have anti-correlated mRNA levels for 50 genes in the 114 and 118 grouping [PMC4175465]. In a network of hub genes/miRNAs, hsa-mir-518c was found to be up-regulated and its target gene was COL1A1 [PMC7851075]. Alterations in hsa-mir-518c have also been observed in various eye diseases, such as retinoblastoma, where it is up-regulated [PMC8669721]. Over-expression of hsa-mir-518c has been observed in acute myeloid leukemia patients [PMC3347893]. In COLO 320 and COLO 205 cells, hsa-mir-518c was found to be up-regulated and involved in the regulation of cell cycle, cell differentiation, migration, and invasion [PMC9941246]. References: - [PMC2831057]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831057/ - [PMC4175465]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175465/ - [PMC7851075]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851075/ - [PMC8669721]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669721/ - [PMC3347893]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347893/ - [PM9941246]: https://www.ncbi.nlm.nih.gov/pmc/articles/PM9941246/